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Study identifier: NCT07584083 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Anifrolumab in Adults With Primary Antiphospholipid Syndrome (AnifAPS Trial)

Condition: Antiphospholipid Syndrome (APS)  ·  Sponsor: National and Kapodistrian University of Athens

PhasePhase 2
Planned participants20
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

This is a phase II, single-centre, open-label pilot study evaluating the safety and tolerability of anifrolumab in adult patients with primary antiphospholipid syndrome (APS). Approximately 20 participants will receive 120 mg subcutaneous anifrolumab once weekly for up to 52 weeks in addition to their standard of care treatment. The primary objective is to assess the incidence of adverse events during treatment. Secondary and exploratory objectives include evaluation of immunological parameters, thromboinflammatory markers, and patient-reported outcomes. Participants will be followed for an additional 12-week safety follow-up period after completion of treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Maria G Tektonidou, MD, PhD  ·  +302107462636  ·  mtektonidou@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Laiko General HospitalAthens, Greece, GreeceRecruiting

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Source record: clinicaltrials.gov/study/NCT07584083