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Study identifier: NCT07577843 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

Condition: Crohn Disease  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 3
Planned participants460
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to assess how well JNJ-78934804 works (efficacy) and how safe it is (safety) as compared to guselkumab at Week 48 in participants with moderately to severely active Crohn's disease (a long-term, progressive \[worsens with time\] and life-threatening disease of the intestine).

This description comes directly from the study's public registry record.

Talk to the study team

Study Contact  ·  844-434-4210  ·  Participate-In-This-Study1@its.jnj.com

Always discuss trial participation with your own doctor first.

Locations (22)

Clinnova ResearchAnaheim, California, United StatesRecruiting
Gastro SB ClinicChula Vista, California, United StatesRecruiting
Peak Gastroenterology AssociatesColorado Springs, Colorado, United StatesRecruiting
Sanchez Clinical Research, IncMiami, Florida, United StatesRecruiting
GCP Clinical ResearchTampa, Florida, United StatesRecruiting
New York Gastroenterology AssociatesNew York, New York, United StatesRecruiting
IBD SAKurralta Park, AustraliaRecruiting
GI Research Institute (G.I.R.I.)Vancouver, British Columbia, CanadaRecruiting
London Digestive Disease InstituteLondon, Ontario, CanadaRecruiting
Bnai Zion Medical CenterHaifa, IsraelRecruiting
Rambam Medical CenterHaifa, IsraelRecruiting
Meir Medical CenterKfar Saba, IsraelRecruiting

+ 10 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07577843