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Study identifier: NCT07577570 Synced from ClinicalTrials.gov · July 29, 2026
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Calcium Replacement Therapy in Postoperative Hypoparathyroidism

Condition: Post-Thyroidectomy Hypoparathyroidism Treatment  ·  Sponsor: Tartu University Hospital

PhaseNA
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate whether a lower-dose calcium replacement therapy is non-inferior to a higher-dose regimen in preventing symptomatic hypoparathyroidism in patients following thyroidectomy. The hypothesis is: • lower-dose calcium replacement therapy is non-inferior to higher-dose therapy in preventing symptomatic hypoparathyroidism during the first two postoperative weeks Researchers will compare patients receiving a lower-dose calcium replacement regimen with those receiving a higher-dose regimen to assess whether the lower dose is not associated with a higher incidence of symptomatic hypoparathyroidism. Patients who develop post-thyroidectomy hypoparathyroidism are divided into groups for calcium replacement therapy. If they are asymptomatic, they will be scheduled for a follow-up visit at two weeks after surgery. During the follow-up visit, calcium metabolism will be evaluated, and treatment adjusted if necessary.

This description comes directly from the study's public registry record.

Talk to the study team

Hanna Hollman  ·  +37259037517  ·  hanna.hollman@ut.ee

Ceith Nikkolo  ·  +372 53318092

Always discuss trial participation with your own doctor first.

Locations (2)

East Tallinn Central HospitalTallinn, Other, EstoniaRecruiting
Tartu University HospitalTartu, EstoniaRecruiting

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Source record: clinicaltrials.gov/study/NCT07577570