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Study identifier: NCT07577232 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Transoral Ultrasound Versus no Transoral Ultrasound in Diagnostic Workup of Peritonsillar Abscess

Condition: Peritonsillar Abscess · Peritonsillar Cellulitis · Tonsillitis  ·  Sponsor: Rigshospitalet, Denmark

PhaseNA
Planned participants368
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Peritonsillar abscess (PTA) is a collection of pus between the palatine tonsil and the constrictor muscle. PTA is detected by recognizing characteristics during clinical examination: redness, pain, malaise, trismus, and unilateral peritonsillar swelling. Clinical assessment, including inspection and palpation, is the traditional diagnostic method for patients suspected of having PTA. If PTA is suspected, aspiration with a large-gauge needle or incision is performed to drain the abscess . It can be challenging to distinguish PTA and peritonsillar cellulitis (PTC) based on clinical examination alone. Due to the increased availability of point-of-care ultrasound, it is a part of the diagnostic workup of PTA. Several studies have shown that transoral US can improve the diagnostic accuracy of patients with a suspected PTA. However, no large multicenter study has evaluated whether one of these methods is superior to the other. It is therefore very clinician-dependent whether the patient will have a transoral US performed or not. The investigators hypothesize that transoral US will increase the diagnostic accuracy of PTA compared to solely clinical examination, which is a visual and palpatory assessment. This will result in fewer unnecessary aspiration attempts and overlooked PTAs. Additionally, the investigators wish to investigate the number of aspirations of transoral US-guided needle aspirations compared to aspirations without ultrasound. Methods This is a cluster randomized st…

This description comes directly from the study's public registry record.

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Locations (3)

Department of Otorhinolaryngology, Head and Neck Surgery & AudiologCopenhagen, DenmarkRecruiting
Department of Otorhinolaryngology, Head and Neck Surgery & Audiology, North Zealand HospitalHillerød, DenmarkRecruiting
Department of ORL - Head & Neck Surgery and Audiology, Zealand University Hospital,Køge, DenmarkNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07577232