Condition: Surgical Stress Response · Inflammation · Anesthesia · Sponsor: Hospital Provincial de Rosario
This randomized controlled trial evaluates whether intraoperative guidance using the CoreSys monitor reduces the surgical stress response in patients undergoing elective open abdominal hysterectomy. Surgical stress involves complex hemodynamic, endocrine, and inflammatory responses that may negatively impact postoperative recovery. Patients will be randomized to either anesthesia guided by conventional clinical and hemodynamic parameters or anesthesia additionally guided by CoreSys-derived indices of consciousness, nociception, and stress activity. The primary objective is to assess whether CoreSys-guided anesthesia attenuates stress biomarkers, including interleukin-6 (IL-6), cortisol and glycemia.
This description comes directly from the study's public registry record.
Mariana I Ciancio, MD · +54 9 341 3007811 · marianacianciow@gmail.com
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| Hospital Provincial de Rosario | Rosario, Santa Fe Province, Argentina | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07571473