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Study identifier: NCT07569549 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy

Condition: Thumb Osteoarthritis · Thumb Carpometacarpal Joint Osteoarthritis · Carpometacarpal (CMC) Joint Arthritis  ·  Sponsor: Uppsala University

PhaseNA
Planned participants84
Who can joinAll sexes, 40 Years to 80 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint osteoarthritis. The main questions it aims to answer are: Does surgery with total joint arthroplasty provide better power grip and pinch grip strength compared to traditional surgery? What is the long-term risk of complications for both methods? Which method is more cost-effective for the healthcare system? Researchers will compare total joint arthroplasty (TOUCH) to trapezectomy (a procedure where a bone in the thumb base is removed) to see which method provides the best results for the patient. Participants will: Be randomized to undergo either an operation with total joint arthroplasty or a trapezectomy. Undergo an initial evaluation and a health economic cost analysis after one year. Attend follow-up checkups at 2, 5, and 10 years post-surgery to evaluate long-term function and the durability of the prosthesis.

This description comes directly from the study's public registry record.

Talk to the study team

Eva Nordin, Clinical research nurse  ·  +46(0) 186119630  ·  eva.nordin@akademiska.se

Elias Gardell, MD, attending hand surgeon  ·  +46 (0) 186171544  ·  elias.gardell@uu.se

Always discuss trial participation with your own doctor first.

Locations (2)

Örebro university hospitalÖrebro, SwedenNot Yet Recruiting
Department of Handsurgery, Uppsala University HospitalUppsala, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT07569549