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Study identifier: NCT07567001 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

Condition: Obesity · Heart Failure  ·  Sponsor: Novo Nordisk A/S

PhasePhase 3
Planned participants5610
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is being done to look at the safety and effect of NNC0487-0111 in people with Heart Failure with preserved Ejection Fraction (HFpEF) or Heart Failure with mildly reduced Ejection Fraction (HFmrEF) and excess body weight when compared to placebo. The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have HFpEF or HFmrEF and excess body weight. Participants will get NNC0487-0111 or placebo by injection once a week. Which treatment participants get is decided by chance. NNC0487-0111 is a new medicine that doctors cannot prescribe yet, but it has been tested in people before.

This description comes directly from the study's public registry record.

Talk to the study team

Novo Nordisk  ·  (+1) 866-867-7178  ·  clinicaltrials@novonordisk.com

Always discuss trial participation with your own doctor first.

Locations (839)

Advanced Cardiovascular, LLCAlexander City, Alabama, United StatesRecruiting
Univ of Alabama BirminghamBirmingham, Alabama, United StatesNot Yet Recruiting
Eastern Shore Rsrch Inst, LLCFairhope, Alabama, United StatesRecruiting
Mobile Heart USA Health Cardiology ClinicMobile, Alabama, United StatesNot Yet Recruiting
Mercy Gilbert Medical CenterGilbert, Arizona, United StatesNot Yet Recruiting
Sun City Clinical ResearchGlendale, Arizona, United StatesRecruiting
Honor HealthPhoenix, Arizona, United StatesNot Yet Recruiting
Arizona Research CenterPhoenix, Arizona, United StatesNot Yet Recruiting
Arkansas Health GroupLittle Rock, Arkansas, United StatesNot Yet Recruiting
InvivoCure -2Alhambra, California, United StatesRecruiting
Cardio Research of S. CalBeverly Hills, California, United StatesRecruiting
Westside Medical Associates Los AngelesBeverly Hills, California, United StatesRecruiting

+ 827 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07567001