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Study identifier: NCT07565493 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Psilocybin Administration With 5-HT1a Blockade

Condition: Psychedelic Effects in Healthy Volunteers  ·  Sponsor: Johns Hopkins University

PhaseEARLY_Phase 1
Planned participants18
Who can joinAll sexes, 21 Years to 60 Years
Healthy volunteersYes

About this study

The purpose of this study is to assess the effects of 5-HT1A receptor blockade on the acute subjective effects of psilocybin, as measured through subjective survey measures and acute electroencephalography (EEG). Further, the investigators will assess the effects of psilocybin on post-acute sleep and dreaming through the use of sleep EEG and sleep and dream diaries.

This description comes directly from the study's public registry record.

Talk to the study team

Zarmeen Zahid, PhD  ·  667-208-8099  ·  psilblock1@jh.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Center for Psychedelics and Consciousness ResearchBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07565493