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Study identifier: NCT07565220 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic Malignancies

Condition: Acute Lymphocytic Leukemia (ALL) · Acute Myeloid Leukemia (AML) · Acute Leukemia  ·  Sponsor: Sawa Ito, MD

PhasePhase 1
Planned participants48
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase 1 trial will investigate the safety and effectiveness of Thiotepa, Busulfan, and Fludarabine (TBF) conditioning regimen with post-transplant cyclophosphamide (PTCy) in HLA-matched related or unrelated donor allogeneic stem cell transplantation (alloSCT).

This description comes directly from the study's public registry record.

Talk to the study team

Amy Rogers, RN, BSN  ·  412-623-4036  ·  rodgera@upmc.edu

Linda Elias, RN, BSN  ·  412-623-6037  ·  eliaslj@upmc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UMPC Hillman Cancer CenterPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07565220