Condition: Esophageal Cancer · Gastric Cancer (Diagnosis) · Upper Gastrointestinal Cancer · Sponsor: Kansai Medical University
This randomized controlled trial aims to determine the optimal exercise intensity for improving postoperative recovery in patients with upper gastrointestinal cancer. Participants who have undergone curative surgery will be randomly assigned to high-intensity interval training (HIIT), low-intensity continuous training (LICT), or usual care. The exercise interventions will be performed under supervision three times per week for eight weeks. The primary outcome is peak oxygen uptake (VO₂peak), assessed using cardiopulmonary exercise testing. Secondary outcomes include physical function, body composition, patient-reported outcomes, and biological and mechanistic markers such as inflammatory biomarkers, muscle-related factors, and gut microbiota. This study will also explore potential mechanisms underlying exercise-induced adaptations and their association with clinical outcomes.
This description comes directly from the study's public registry record.
Takuya Fukushima · +81-72-856-2115 · fukushima.tky@kmu.ac.jp
Jiro Nakano · +81-72-856-2115 · nakano.jir@kmu.ac.jp
Always discuss trial participation with your own doctor first.
| Kansai Medical University | Hirakata, Osaka, Japan | Not Yet Recruiting |
| Kansai Medical University | Hirakata, Osaka, Japan | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07561840