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Study identifier: NCT07561541 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Extended Oral Antibiotic Prophylaxis in Diabetic Fracture Patients

Condition: Fracture Lower Leg · Diabetes · Fracture Fixation, Internal  ·  Sponsor: Texas Tech University Health Sciences Center, El Paso

PhasePhase 4
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if taking an antibiotic pill for 7 days after surgery reduces the risk of wound infection in adults with poorly controlled diabetes who have surgery to fix a broken bone in the leg, ankle, or foot. It will also learn about the safety of the extended antibiotic course. The main questions it aims to answer are: Does a 7-day antibiotic course after surgery lower the rate of wound infection within 90 days? What medical problems do participants have when taking the extended antibiotic course? Researchers will compare a 7-day course of an oral antibiotic (cefadroxil) to standard care (no additional antibiotics after surgery) to see if the extended course reduces infections. Participants will: Take an antibiotic pill or receive standard care for 7 days after surgery Receive a phone call from the study team about 1 week after surgery Visit the clinic at 3 weeks, 6 weeks, and 3 months after surgery for checkups

This description comes directly from the study's public registry record.

Talk to the study team

Taylor M Yong, MD, MS  ·  915-215-5480  ·  tayong@ttuhsc.edu

Always discuss trial participation with your own doctor first.

Locations (3)

University of Southern CaliforniaLos Angeles, California, United StatesRecruiting
University Medical Center of El PasoEl Paso, Texas, United StatesRecruiting
Texas Tech Health El PasoEl Paso, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07561541