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Study identifier: NCT07559786 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Multicenter, Open-label, Randomized, Prospective Clinical Study of Adebrelimab Consolidation Therapy for Limited-Stage Small-Cell Lung Cancer (LS-SCLC) Without Progression After Concurrent Chemoradiotherapy

Condition: SCLC, Limited Stage  ·  Sponsor: Henan Cancer Hospital

PhasePhase 2
Planned participants200
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study aims to evaluate the efficacy and safety of adebrelimab consolidation therapy after progression-free response of concurrent chemoradiotherapy in patients with limited-stage small cell lung cancer. This study plans to enroll patients with untreated limited-stage small cell lung cancer who meet the inclusion criteria. The eligible patients will be randomly divided 1:1 into two groups to receive treatment regimens for residual lymph nodes and involved irradiated areas. That is, carboplatin AUC 5, D1 + etoposide 100 mg/m…\^2 on days 1, 2, and 3 + thoracic radiotherapy (residual lymph nodes or involved irradiated areas), with each 3-week cycle. After 4 cycles of concurrent chemoradiotherapy, the non-progressing subjects will continue to receive adebrelimab (1200 mg, IV, Q3W) maintenance therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Qingminf QM Wang, Professor  ·  +8613783590691  ·  qimingwang1006@126.com

Always discuss trial participation with your own doctor first.

Locations (2)

Henan Cancer HospitalZhengzhou, Henan, ChinaNot Yet Recruiting
Henan Cancer HospitalZhengzhou, Henan, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07559786