Condition: Advanced Colorectal Cancer · Sponsor: University Hospital, Antwerp
The FOLICOLOR trial aims to evaluate whether a liquid biopsy-guided follow-up strategy can improve outcomes in patients with unresectable, metastatic colorectal cancer (mCRC) receiving first-line systemic treatment. The approach uses NPY methylation-based circulating tumor DNA (ctDNA) analysis from blood samples to monitor treatment response and guide clinical decision-making. Eligible patients are adults diagnosed with unresectable, metastatic colorectal cancer who are starting first-line treatment. The primary goal is to demonstrate a clinically meaningful benefit, particularly in terms of quality of life (QoL) and reduction of treatment-related toxicity, by allowing earlier and more personalized therapeutic adjustments based on liquid biopsy findings.
This description comes directly from the study's public registry record.
Sanne Wouters · 003238212441 · sanne.wouters@uza.be
Ayla Wyninckx · 003232759745 · ayla.wyninckx@uza.be
Always discuss trial participation with your own doctor first.
| AZ Sint Maarten | Mechelen, Antwerpen, Belgium | Recruiting |
| AZ Klina | Brasschaat, Antwerp, Belgium | Recruiting |
| University Hospital Antwerp | Edegem, Antwerp, Belgium | Recruiting |
| Sint-Augustinus (ZAS) | Wilrijk, Antwerp, Belgium | Recruiting |
| Grand Hopital de Charleroi | Charleroi, Henegouwen, Belgium | Recruiting |
| AZ Maria Middelares, Ghent | Ghent, Oost-Vlaanderen, Belgium | Recruiting |
| Vitaz | Sint-Niklaas, Oost-Vlaanderen, Belgium | Recruiting |
| AZ Sint Lucas, Brugge | Bruges, West-Vlaanderen, Belgium | Recruiting |
| AZ Groeninge, Kortrijk | Kortrijk, West-Vlaanderen, Belgium | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07558083