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Study identifier: NCT07557017 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Unified Protocol for Emotional Disorders: HiTOP-PRO Trial

Condition: Emotional Disorder  ·  Sponsor: National Institute of Mental Health, Czech Republic

PhaseNA
Planned participants90
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This randomised, parallel-group clinical trial evaluates the effects of the Unified Protocol (UP), a transdiagnostic cognitive-behavioural psychotherapy, on dimensional symptom outcomes aligned with the Hierarchical Taxonomy of Psychopathology (HiTOP) and on related temperamental/personality traits in adults with emotional disorders. Participants are randomly assigned (1:1:1) to UP, treatment as usual (TAU), or a waitlist (WL). Outcomes are assessed at baseline and after approximately 14 weeks. A planned follow-up assessment approximately 3 months after treatment completion is collected in the UP arm only.

This description comes directly from the study's public registry record.

Talk to the study team

Eva Dreyfus, MSc.  ·  +420283088282  ·  eva.dreyfus@nudz.cz

Always discuss trial participation with your own doctor first.

Locations (1)

National Institute of Mental healhPrague, CzechiaRecruiting

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Source record: clinicaltrials.gov/study/NCT07557017