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Study identifier: NCT07554833 Synced from ClinicalTrials.gov · July 29, 2026
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Effects of Accelerated rTMS On Motor and Cognitive Function in Parkinson's Disease

Condition: PARKINSON DISEASE (Disorder) · Parkinson s Disease  ·  Sponsor: San Francisco Neurology and Sleep Center

PhaseNA
Planned participants40
Who can joinAll sexes, 50 Years to 90 Years
Healthy volunteersNo

About this study

Parkinson's disease (PD) is a brain disorder that causes progressive problems with movement, such as slowness, stiffness, tremor, and difficulty walking. Many people with PD also develop problems with thinking and memory. Current medications can help control movement symptoms but often become less effective over time and may cause side effects. There is a need for additional treatment options that can address both movement and thinking difficulties in PD. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive treatment that uses magnetic pulses delivered to the scalp to stimulate specific areas of the brain. Previous research has shown that rTMS targeting the motor cortex (the part of the brain that controls movement) can improve motor symptoms in people with PD. The purpose of this pilot study is to evaluate whether an accelerated course of rTMS targeting the motor cortex can improve movement and thinking abilities in people with mild to moderate Parkinson's disease. The study will enroll 40 participants aged 50 to 90 years at the San Francisco Neurology and Sleep Center. Participants will receive 6 sessions of rTMS using the EXOMIND™ device, administered twice per week over approximately 3 weeks. Each session delivers high-frequency magnetic stimulation to the motor cortex on both sides of the brain. Participants will be assessed before treatment, at the last treatment session, and at 1-month and 3-month follow-up visits. The primary outcome measure is th…

This description comes directly from the study's public registry record.

Talk to the study team

Joy Shihui Meng, MD  ·  415-666-2536  ·  joymengmd@sf-neurology.com

Junyi Sun, MD, PhD  ·  628-249-5656  ·  office@sf-neurology.com

Always discuss trial participation with your own doctor first.

Locations (1)

San Francisco Neurology and Sleep CenterSan Francisco, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07554833