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Study identifier: NCT07554820 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Major Adverse Cardiovascular Events (MACE) in Rheumatoid Arthritis Patient With Moderate to Severe Disease Activity Treated With Tofacitinib and Statins vs TNF Inhibitors: TOFSTAT CLINICAL TRIAL

Condition: Rheumatoid Arthritis · Major Adverse Cardiac Events  ·  Sponsor: Shaikh Zayed Hospital, Lahore

PhasePhase 4
Planned participants120
Who can joinAll sexes, 50 Years to 85 Years
Healthy volunteersNo

About this study

The rationale of our study is to observe the incidence of MACE in RA patients treated with tofacitinib along with statins with one or more cardiovascular disease risks. PRIMARY OBJECTIVE * To determine the incidence of MACE in Rheumatoid Arthritis patients with moderate to high disease activity and with one or more cardiovascular disease risks, which are non-responsive to standard conventional DMARDs (cDMARDs) treatment and are prescribed Tofacitinib 5 mg twice daily along with statin 20 mg daily versus TNF Inhibitors. * The study aim to compare MACE in RA patients treated with tofacitinib and statin versus TNF inhibitors.

This description comes directly from the study's public registry record.

Talk to the study team

Masooma Hashmat, FCPS Rheumatology  ·  +923353053304  ·  masoomahashmat@gmail.com

Aflak Rasheed, FCPS Rheumatology  ·  +923009476913  ·  aflakrasheed@yahoo.com

Always discuss trial participation with your own doctor first.

Locations (1)

Shaikh Zayed Hospital, LahoreLahore, Punjab Province, PakistanRecruiting

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Source record: clinicaltrials.gov/study/NCT07554820