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Study identifier: NCT07554664 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Central Sensitization, Work-Related Stress, and Musculoskeletal Symptoms in Desk-Based Workers With and Without Migraine

Condition: Migraine · Worker Health · Sensitization  ·  Sponsor: Bozok University

PhaseN/A
Planned participants159
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

Migraine is a common neurological disease causing significant disability worldwide, with an estimated global prevalence of 14.4%. It represents a significant individual and societal burden, particularly for working-age individuals, as it can significantly impact work performance, productivity, and daily living activities. Migraine is not merely a headache; it is characterized by increased excitability of neurons in the central nervous system, leading to hypersensitivity to pain. Central sensory mechanisms are thought to play a role in the pathophysiology and chronicity of migraine, causing increased pain sensitivity, allodynia, and potentially related to musculoskeletal pain. Furthermore, psychosocial factors and work stress have been identified as significant factors associated with both headaches and musculoskeletal pain. Literature indicates that neck pain is common in individuals with migraine headaches; in fact, neck pain is twice as frequent in patients with chronic migraine headaches compared to those with episodic migraine. While evidence regarding back pain is limited, it has been shown that individuals with chronic headaches report back pain more frequently. In modern work environments, sedentary work and prolonged computer use are increasing. Prolonged sitting, improper ergonomics, and repetitive movements are considered significant risk factors for musculoskeletal problems. This can lead to pain and functional limitations, particularly in the neck, shoulders, and…

This description comes directly from the study's public registry record.

Talk to the study team

Dilara ONAN, PhD  ·  +905358642234  ·  dilaraonan@gmail.com

Pelin YENİLMEZ YEŞİLDAŞ, Neurologist  ·  +905392040612  ·  pelinnyenilmez@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Gaziantep City HospitalGaziantep, Merkez, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07554664