Condition: Parkinsonism · REM Sleep Behavior Disorder · Sponsor: Ruijin Hospital
This is a single-center, prospective, observational cohort study designed to investigate the progression and differential diagnosis of Parkinsonism using a multimodal approach. The study plans to enroll 400 patients with Parkinsonism, 120 patients with rapid eye movement sleep behavior disorder, and 120 healthy controls, with follow-up for 5 years. Assessments will include neuroimaging, clinical rating scales, biological samples, blood flow evaluation, neurophysiological testing, tremor analysis, and voice and video assessments. The study aims to characterize disease progression, explore factors associated with progression from rapid eye movement sleep behavior disorder to Parkinsonism, and improve the ability to distinguish among different Parkinsonian disorders.
This description comes directly from the study's public registry record.
Jun Liu, Professor · +86-021-64370045 · lj11128@rjh.com.cn
Always discuss trial participation with your own doctor first.
| Department of neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine | Shanghai, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07553845