Condition: Palliative Care · Breathlessness · Sponsor: Tampere University Hospital
Dyspnea in patients with incurable illness is a difficult symptom. Therefore, there is a need to identify new effective treatment modalities. Previous studies suggest that high-flow nasal therapy delivered via a nasal cannula (HFNT = High-Flow Nasal Therapy) may alleviate dyspnea, and similarly that directing airflow toward the face can provide relief. HFNT has been studied very little in hospice settings and on palliative care wards. The aim of this study is to determine whether HFNT is a feasible and effective treatment for relieving dyspnea in patients receiving palliative care. Patients will be recruited from the Hatanpää Palliative Care Ward and the Pirkanmaa Hospice, Tampere, Finland. The target is to recruit approximately 30-40 patients. The inclusion criteria are: age ≥18 years, ability to understand the study and provide informed consent to participate, a palliative treatment approach, and significant dyspnea. Each patient receives HFNT and fan therapy in which airflow will be directed toward the patient's face. Both treatments will last 30 minutes. Patient symptoms will be asked after the treatments. In addition, patients will be asked to rate the overall benefit they experienced from the intervention and any side effects. The primary endpoint is the relief of dyspnea with HFNT compared with fan therapy. The study will be conducted in accordance with laws, regulations, and guidelines governing medical research, as well as good scientific practice and research eth…
This description comes directly from the study's public registry record.
Juho Lehto, Professor · +358 50 4090974 · juho.lehto@tuni.fi
Sirpa Leivo-Korpela, MD, PhD · + 358 44 485 8055 · sirpa.leivo-korpela@pirha.fi
Always discuss trial participation with your own doctor first.
| Pirkanmaa Hospice | Tampere, Finland | Recruiting |
| Hatanpää hospital, Palliative Care Centre and Home Hospital Services, Wellbeing Services County of Pirkanmaa, Tampere University Hospital | Tampere, Finland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07552935