Condition: Liver Transplant · Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
This is a prospective multi-center, longitudinal study to determine efficacy of 50 percent Immunosuppression (IS) reduction. One hundred fully eligible participants will reduce IS by 50 percent in two steps. Liver tests will be checked every 0.5 months through month 4, once a month through month 12, and every other month through month 18. Liver transplant (LTx) center visits will take place at screening, months 6, 12 and 18 after initiating IS dose reduction. A protocol driven liver biopsy to adjudicate the endpoint will be performed at 18 months. The duration of the study from time of starting IS dose reduction to the primary endpoint assessment is 18 months. The primary objective is to assess the efficacy of 50 percent IS dose reduction in children with Liver transplants (LTxs)
This description comes directly from the study's public registry record.
Ada Chao · 415-353-7004 · ada.chao@ucsf.edu
Always discuss trial participation with your own doctor first.
| UCSF Benioff Children's Hospital | San Francisco, California, United States | Not Yet Recruiting |
| Children's Hospital Colorado | Aurora, Colorado, United States | Not Yet Recruiting |
| MedStar Georgetown University Hospital | Washington D.C., District of Columbia, United States | Not Yet Recruiting |
| Emory University School of Medicine/Children's Healthcare of Atlanta | Atlanta, Georgia, United States | Not Yet Recruiting |
| Ann and Robert H. Lurie Children's Hospital of Chicago | Chicago, Illinois, United States | Recruiting |
| Icahn School of Medicine at Mount Sinai | New York, New York, United States | Not Yet Recruiting |
| Columbia University Medical Center | New York, New York, United States | Not Yet Recruiting |
| Cincinnati Children's Hospital Medical Center | Cincinnati, Ohio, United States | Recruiting |
| Children's Hospital of Philadelphia | Philadelphia, Pennsylvania, United States | Not Yet Recruiting |
| Monroe Carell Jr. Children's Hospital at Vanderbilt | Nashville, Tennessee, United States | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT07549503