Condition: Type 2 Diabetes · Sponsor: Housey Healthcare ULC
Blood sugar levels are controlled by insulin, a hormone made by cells in the pancreas. After a meal, carbohydrates are broken down into glucose which is absorbed from the intestine into the blood leading to a rise in glucose (blood sugar) which triggers the secretion of insulin. Insulin binds to cells in several tissues including liver, muscle, and fat, triggering cells to take up glucose and bring the blood glucose level back to normal. A high blood sugar level is known as diabetes. The most common form of diabetes, type 2 diabetes, is caused by insulin resistance; that is, a reduced ability of insulin to stimulate glucose uptake into cells. The body compensates for insulin resistance by making more insulin; type 2 diabetes occurs when the pancreas can no longer make enough insulin to control blood glucose. The high blood glucose and insulin levels lead to long-term complications such as heart attacks, kidney failure, reduced sensation and poor circulation in the feet and legs. High insulin levels also increase the incidence of cancers, stroke, and dementia. Reducing blood glucose levels with oral medications and insulin reduces risk of diabetic complications. There are several types of oral medications available for treating diabetes; however, they do not always control blood glucose adequately. In addition, these drugs have complications and are not used to treat insulin resistance and prediabetes - a condition when blood glucose is higher than normal but not high enough…
This description comes directly from the study's public registry record.
Housey Study Info · (248) 663-7000 · StudyInfo@housey.com
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| AMR Clinical - El Dorado | El Dorado, Kansas, United States | Recruiting |
| Tandem Clinical Research (Interspond) | Marrero, Louisiana, United States | Recruiting |
| Arcturus Healthcare, PLC, Troy Internal Medicine Research Division | Troy, Michigan, United States | Recruiting |
| Velocity Clinical Research Norfolk | Norfolk, Nebraska, United States | Recruiting |
+ 13 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07546929