← Eichor
Study identifier: NCT07545395 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety of KN057 Prophylaxis in Patients With Haemophilia A or B

Condition: Hemophilia A or B  ·  Sponsor: Suzhou Alphamab Co., Ltd.

PhasePhase 3
Planned participants70
Who can joinMale, 12 Years to 65 Years
Healthy volunteersNo

About this study

The purposes of this open-label, multicenter III clinical trial are to evaluate the safety and efficacy of long-term preventive treatment with KN057 in Haemophilia A or B patients with or without inhibitors, and to assess the pharmacokinetic characteristics of the new and old processes KN057. The participants in Part PK will be randomly assigned to Old process Group or New process Group in a 1:1 ratio. The participants in Old process Group will receive old process KN057 prophylaxis for the first 26 weeks and new process KN057 prophylaxis for the following 26 weeks. The participants in New process Group will receive new process KN057 prophylaxis for both the first 26 weeks and the last 26 weeks. The participants in Part non-PK will be non-randomized and treated with new process KN057 for 52 weeks prophylaxis after enrollment. Priority screening and enrollment of participants who have participated in the KN057-A-301 or KN057-A-302 study.

This description comes directly from the study's public registry record.

Talk to the study team

Yanrong Dong, Master  ·  +86 18914005458  ·  yanrongdong@alphamab.com

Always discuss trial participation with your own doctor first.

Locations (1)

Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical SciencesTianjin, Tianjin Municipality, ChinaRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07545395