Condition: Colorectal Cancer · Gastric Adenocarcinoma · Esophageal Adenocarcinoma · Sponsor: Dispatch Biotherapeutics
This is a Phase 1, multicenter, open-label study of DISP-10, a combination therapy consisting of DV-10 (adenovirus) and idecabtagene vicleucel (ide-cel, BCMA-directed chimeric antigen receptor \[CAR\] T), in adult participants with advanced gastrointestinal (GI) cancers. The study will consist of 2 parts: dose-escalation (Part 1) and dose-expansion (Part 2). Part 1 of the study will evaluate the safety and tolerability of increasing dose levels of DISP-10 to establish the recommended dose for expansion (RDE); Part 2 will evaluate the safety and efficacy of DISP-10 in participants treated at the RDE.
This description comes directly from the study's public registry record.
Dispatch Clinical · (215) 792-4699 · clinicaltrials@dispatchbio.com
Always discuss trial participation with your own doctor first.
| City of Hope | Duarte, California, United States | Recruiting |
| University of Cincinnati Cancer Center | Cincinnati, Ohio, United States | Recruiting |
| Tennessee Oncology | Nashville, Tennessee, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07544589