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Study identifier: NCT07541079 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study Evaluating Adherence, Tolerability, and Patient Reported Outcomes of Giredestrant in Participants With ER+/HER2- Early Breast Cancer Who Are Intolerant to Adjuvant Aromatase Inhibitor Therapy (novERA Breast Cancer)

Condition: Early Breast Cancer  ·  Sponsor: Genentech, Inc.

PhasePhase 3
Planned participants300
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to understand treatment adherence and patient-reported outcomes of switching to giredestrant due to prior aromatase inhibitor (AI) intolerance. Giredestrant will be administered as adjuvant endocrine therapy for participants with low-, medium-, and high-risk, Stage I-III, histologically confirmed, estrogen receptor positive (ER+), human epidermal growth factor receptor 2 negative (HER2-), early breast cancer (eBC), as defined by the investigator. Participants will enroll if considered to be intolerant to a prior adjuvant AI therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: GO46747 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728 (U.S. Only)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (1)

Orange Coast Medical CenterFountain Valley, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07541079