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Study identifier: NCT07540741 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Efficacy and Safety of PCSK9 Inhibitors in Patients With Large-Artery Atherosclerosis (LAA) Ischemic Stroke

Condition: Acute Ischemic Stroke  ·  Sponsor: First Affiliated Hospital of Harbin Medical University

PhaseN/A
Planned participants1000
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This prospective multicenter cohort study aims to evaluate the effectiveness and safety of early PCSK9 inhibitor therapy in patients with large-artery atherosclerotic ischemic stroke. The study will compare early neurological improvement, lipid-lowering effect, 90-day functional outcome, recurrent cardio-cerebrovascular events, and safety outcomes between patients treated with evolocumab plus statin and those treated with statin alone.

This description comes directly from the study's public registry record.

Talk to the study team

Zhongling Zhang  ·  +8613503615988  ·  zhang777hyd@163.com

Shanshan Yang  ·  +8613845104003  ·  yangshanshan81@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Harbin, Heilongjiang, China, 150001Heilongjiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07540741