Condition: Septic Shock · Multiorgan Failure · Sepsis · Sponsor: Seoul National University Bundang Hospital
This study aims to evaluate the clinical effectiveness of the oXiris® hemofilter in patients with septic shock and acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT). While some studies suggest that oXiris® may improve hemodynamic stability by removing endotoxins and cytokines, its impact on survival remains inconsistent.To provide more reliable causal evidence, this multicenter retrospective cohort study utilizes a Target Trial Emulation (TTE) approach. The study will compare patients treated with the oXiris® filter to those treated with standard CRRT filters, focusing on in-hospital mortality and other clinical outcomes such as fluid balance and vasopressor requirements.
This description comes directly from the study's public registry record.
Sung Yoon Lim, MD. PhD · 82+1028469179 · nucleon727@snu.ac.kr
Myung Jin Song, MD.PhD · 82+1045990531 · mjsong8705@gmail.com
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| Seoul National University Bundang Hospital | Seongnam-si, Gyeonggi-do, South Korea | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07539883