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Study identifier: NCT07537296 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Coronary and Myocardial Evaluation by Cardiac CT for Acute Myocardial Infarction

Condition: Acute Myocardial Infarction (AMI)  ·  Sponsor: Nanjing First Hospital, Nanjing Medical University

PhaseN/A
Planned participants1000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Acute myocardial infarction (AMI) remains a major cause of mortality and morbidity worldwide. Although percutaneous coronary intervention (PCI) combined with guideline-directed medical therapy has substantially improved survival, many patients continue to experience adverse cardiovascular events after revascularization, including recurrent ischemic events, heart failure, and malignant arrhythmias. Therefore, accurate risk stratification after PCI is essential for optimizing clinical management and improving long-term outcomes. However, currently available risk prediction tools are limited by suboptimal predictive performance or restricted clinical accessibility. Cardiac imaging plays a central role in post-AMI evaluation. Echocardiography is routinely recommended after PCI to assess cardiac structure and function and to exclude early mechanical complications. Nevertheless, its ability to predict subsequent ventricular remodeling and long-term clinical outcomes is limited. Cardiac magnetic resonance imaging (CMR) is considered the reference standard for myocardial tissue characterization and provides important prognostic markers such as infarct size, microvascular obstruction, and intramyocardial hemorrhage. However, the routine use of CMR in patients with AMI is constrained by limited availability, high cost, and relatively long examination time. In addition, CMR does not directly evaluate coronary artery anatomy or plaque characteristics, which are important determinants of…

This description comes directly from the study's public registry record.

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Locations (2)

Nanjing First Hospital, Nanjing Medical University, 68 Changle road, Qinhuai DistrictNanjing, Jiangsu, ChinaRecruiting
Nanjing First Hospital, Nanjing Medical University, 68 Changle road, Qinhuai DistrictNanjing, Jiangsu, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07537296