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Study identifier: NCT07533175 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

Condition: Diabetes Mellitus · Overweight · Obesity  ·  Sponsor: Novo Nordisk A/S

PhasePhase 3
Planned participants630
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight and type 2 diabetes. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111 (the treatment being tested) or Placebo (treatment that has no active medicine in it). Which treatment participants get is decided by chance.

This description comes directly from the study's public registry record.

Talk to the study team

Novo Nordisk  ·  (+1) 866-867-7178  ·  clinicaltrials@novonordisk.com

Always discuss trial participation with your own doctor first.

Locations (74)

Univ of Alabama BirminghamBirmingham, Alabama, United StatesRecruiting
Headlands Research California, LLCEscondido, California, United StatesRecruiting
Torrance Clinical Research Institute, Inc.Lomita, California, United StatesRecruiting
Diablo Clinical Research, Inc.Walnut Creek, California, United StatesRecruiting
Northeast Research InstituteFleming Island, Florida, United StatesRecruiting
Jacksonville Ctr Clin ResJacksonville, Florida, United StatesRecruiting
Florida Institute for Clinical Research, LLCOrlando, Florida, United StatesRecruiting
Oviedo Medical Research, LLCOviedo, Florida, United StatesRecruiting
International Diabetes CenterMinneapolis, Minnesota, United StatesRecruiting
Southgate Medical Group, LLPWest Seneca, New York, United StatesRecruiting
Spartanburg Medical ResearchSpartanburg, South Carolina, United StatesRecruiting
M3 Wake Research ChattanoogaChattanooga, Tennessee, United StatesRecruiting

+ 62 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07533175