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Study identifier: NCT07532629 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Microbiome and Metabolome Profiles in Couples Undergoing IVF and Reproductive Outcomes

Condition: Infertility · Assisted Reproductive Technology · Pregnancy Complications  ·  Sponsor: Karolinska Institutet

PhaseN/A
Planned participants1000
Who can joinAll sexes, 18 Years to 40 Years
Healthy volunteersYes

About this study

This prospective observational cohort study investigates the role of the microbiome and metabolome in couples undergoing in vitro fertilization. Biological samples will be collected from both female and male partners, including semen, vaginal, and blood samples, to characterize microbial composition and metabolic profiles. The study aims to examine how these biological profiles are associated with reproductive outcomes such as fertilization, pregnancy, miscarriage, and live birth. Participants will be followed longitudinally, and reproductive and obstetric outcomes will be obtained through linkage with national health registers.

This description comes directly from the study's public registry record.

Talk to the study team

Ola Larsson, PhD  ·  +46 8 524 80000  ·  ola.larsson@ki.se

Hanna Nilsson, PhD  ·  hanna.nilsson@ki.se

Always discuss trial participation with your own doctor first.

Locations (3)

Reproduktionsmottagning Malmö, Skånes universitetssjukhusMalmö, SwedenRecruiting
Karolinska UniversitetssjukhusetStockholm, SwedenRecruiting
Reproduktionscenter, Akademiska sjukuhsetUppsala, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT07532629