Condition: Cardiac Disease · Multiple Organ Dysfunction Syndrome · Sponsor: Efferon JSC
This randomized controlled study aims to evaluate the efficacy and safety of intraoperative and early postoperative hemoadsorption using the Efferon® LPS device in patients undergoing cardiac surgery with cardiopulmonary bypass in reducing the incidence and severity of multiple organ dysfunction syndrome (MODS) in the postoperative period. Each patient in the treatment group will undergo two hemoadsorption sessions: first during cardiopulmonary bypass (CPB) at the time of cardiac surgery, with the duration determined by the CPB time, and second within 24 hours postoperatively, for a minimum duration of 6 hours.
This description comes directly from the study's public registry record.
Alexandr Shelehov-Kravchenko, PhD, MD · +79636564765 · ais@efferon.ru
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| Regional State Budgetary Healthcare Institution "Altai Regional Cardiological Dispensary" | Barnaul, Russia | Recruiting |
| Almazov National Medical Research Centre | Saint Petersburg, Russia | Recruiting |
| Pavlov First Saint Petersburg State Medical University | Saint Petersburg, Russia | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07532174