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Study identifier: NCT07532161 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Comparison Between Liquid Fibrin and Soft Laser Effects on Healing and Relapse After Lip Repositioning Surgery

Condition: Gummy Smile  ·  Sponsor: Damascus University

PhaseNA
Planned participants22
Who can joinAll sexes, 18 Years to 50 Years
Healthy volunteersNo

About this study

A gummy smile can negatively affect a patient's self-confidence and satisfaction with their appearance, leading many individuals to seek effective esthetic solutions. The etiology of this condition varies and may include vertical maxillary excess, short upper lip, hyperactive upper lip, gingival enlargement, or altered passive eruption. Lip Repositioning Surgery is one of the minimally invasive esthetic surgical procedures used to reduce the amount of gingival display during smiling. Despite its effectiveness, this surgery may be associated with challenges such as pain, swelling, delayed wound healing, and the possibility of postoperative relapse over time, which could compromise both esthetic and functional outcomes. To overcome these challenges and enhance surgical outcomes, adjunctive techniques have been introduced to promote healing and determine whether enhancing the biological healing process can reduce the rate of relapse after LRS. Among the most prominent of these are Injectable Platelet-Rich Fibrin (i-PRF) and Low-Level Laser Therapy (LLLT).

This description comes directly from the study's public registry record.

Talk to the study team

Tarek Qasem, DDS MSc PhD  ·  +963 933432778  ·  Tarek2.qasem@damascusuniversity.edu.sy

Walaa albarry, DDS  ·  +963 996766302  ·  walaa9.albarry.@damascusuniversity.edu.sy

Always discuss trial participation with your own doctor first.

Locations (1)

Faculty of Dentistry, Damascus university , Syria.Damascus, Rif-dimashq Governorate, SyriaRecruiting

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Source record: clinicaltrials.gov/study/NCT07532161