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Study identifier: NCT07529717 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

First-in-Human Study to Evaluate AZD8359 STEAP2 TCE in Participants With Prostate Cancer

Condition: Metastatic Prostate Cancer  ·  Sponsor: AstraZeneca

PhasePhase 1/Phase 2
Planned participants42
Who can joinMale, 18 Years to 100 Years
Healthy volunteersNo

About this study

This study is being conducted to learn more about the safety, tolerability, and effectiveness of an experimental treatment for metastatic prostate cancer called AZD8359. The study is split into different modules which will look at AZD8359 delivered by different methods. The study is also further split into 2 parts, Part A which will test different dose levels and dosing schedules of AZD8359 to determine which doses are the best in terms of safety and side effects (dose escalation), and Part B will further test at least two AZD8359 doses in a larger group of participants (dose expansion).

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (8)

Research SiteOrlando, Florida, United StatesRecruiting
Research SiteEast Brunswick, New Jersey, United StatesRecruiting
Research SiteHackensack, New Jersey, United StatesNot Yet Recruiting
Research SiteProvidence, Rhode Island, United StatesNot Yet Recruiting
Research SiteDarlinghurst, AustraliaNot Yet Recruiting
Research SiteMelbourne, AustraliaRecruiting
Research SiteSeoul, South KoreaRecruiting
Research SiteSeoul, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT07529717