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Study identifier: NCT07529379 Synced from ClinicalTrials.gov · July 28, 2026
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Breathwork and Stress: Investigating the Mechanisms of Action and Effectiveness of Breathing Interventions in Modulating the Psychophysiological Response to Acute Stress Test

Condition: Healthy Adult Participants · Acute Stress Reaction · Stress Biomarkers  ·  Sponsor: Medical University of Bialystok

PhaseNA
Planned participants120
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersYes

About this study

This study investigates whether the psychophysiological benefits of breathing exercises are driven by a specific physiological rhythm (6 breaths per minute) or by the general psychological experience of performing a structured, mindful activity. Researchers aim to determine if "coherent breathing", which is hypothesized to synchronize heart and respiratory rhythms, offers unique physiological protection against stress compared to breathing at a natural pace or simple resting. The main questions it aims to answer are: * Does slow, steady breathing at 6 breaths per minute lower physical stress markers (like heart rate variability and cortisol) better than faster, but structured breathing or just sitting still? * Is the calming effect caused by the specific breathing rhythm or simply by performing a structured, relaxing activity? Researchers will compare three groups to see if the specific rhythm of "coherent breathing" offers unique benefits: 1. Group (Interventional): Coherent Breathing: Slow breathing at 6 breaths per minute. 2. Group (Sham Breathing): Regular breathing at 15 breaths per minute (matching a natural pace). 3. Spontaneous Breathing (Control Group): Natural, unguided breathing. Participants will: * Complete a one-day preparation phase to become familiar with the breathing technique. * Visit the research center for one experimental session. * Perform their assigned breathing method before and after a stress test. * Take the Maastricht Acute Stress Test (MAST)…

This description comes directly from the study's public registry record.

Talk to the study team

Adam Siebieszuk, Master  ·  +48 85 748 55 85  ·  adam.siebieszuk@sd.umb.edu.pl

Always discuss trial participation with your own doctor first.

Locations (1)

Medical University of Bialystok. Department of Physiology.Bialystok, Podlaskie Voivodeship, PolandRecruiting

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Source record: clinicaltrials.gov/study/NCT07529379