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Study identifier: NCT07528183 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Maintenance Immunotherapy With Deferred Salvage Radiotherapy After Response to Chemoimmunotherapy in Recurrent Nasopharyngeal Carcinoma

Condition: Nasopharyngeal Cancinoma (NPC)  ·  Sponsor: Sun Yat-sen University

PhasePhase 2
Planned participants62
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

Re-irradiation is the most common clinical treatment for recurrent nasopharyngeal carcinoma; however, it is associated with severe complications which seriously affect patients' quality of life. Exploring deferred salvage radiotherapy until nasopharyngeal or cervical progression after PD 1 plus GP chemotherapy and immunotherapy maintenance is of great significance for improving the long-term survival and quality of life of patients with unresectable locally recurrent NPC. Thus, the investigators plan to conduct a multicenter, prospective, single-arm phase II clinical trial to evaluate the efficacy and safety of maintenance Immunotherapy with deferred salvage radiotherapy with an objective response to chemoimmunotherapy in patients with unresectable locally recurrent NPC .

This description comes directly from the study's public registry record.

Talk to the study team

Haiqiang Mai  ·  +86-20-87343380  ·  maihq@sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (4)

Fujian Cancer HospitalFuzhou, Fujian, ChinaNot Yet Recruiting
Sun Yat-sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting
Guangxi Medical University Cancer HospitalNanning, Guangxi, ChinaNot Yet Recruiting
Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyWuhan, Hubei, ChinaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07528183