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Study identifier: NCT07528066 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Downstaging and RATS After Neo-Chemo-IO: Impact on Surgical Outcomes in NSCLC

Condition: Neoadjuvant Chemoimmunotherapy · Robotic Pulmonary Resection · Stage IIB-III NSCLC  ·  Sponsor: Shanghai Chest Hospital

PhaseN/A
Planned participants200
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to learn whether tumor and nodal downstaging after neoadjuvant chemo-immunotherapy is associated with better surgical outcomes in patients with clinical stage IIB-III non-small cell lung cancer (NSCLC) undergoing robotic-assisted thoracic surgery. The main question it aims to answer is: Is downstaging after neoadjuvant chemo-immunotherapy associated with better surgical outcomes in patients with stage IIB-III NSCLC undergoing robotic-assisted surgery? Participants with resectable or potentially resectable stage IIB-III NSCLC who receive neoadjuvant chemo-immunotherapy as part of their routine clinical care and then undergo curative-intent robotic-assisted surgery will be prospectively enrolled from international centers. Clinical, operative, pathological, and postoperative outcome data will be collected, including R0 resection, the extent of resection, conversion to open surgery, postoperative complications, length of stay, readmission, and mortality.

This description comes directly from the study's public registry record.

Talk to the study team

Zhigang Li, MD, PhD  ·  0086-021-22200000  ·  zhigang.li@shsmu.edu.cn

Lin Huang, MD, PhD  ·  0086-18116061178  ·  dr.huang.lin@shsmu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (10)

Fujian Medical University Union HospitalFuzhou, Fujian, ChinaRecruiting
Guangdong Provincial People's HospitalGuangzhou, Guangdong, ChinaRecruiting
Shenzhen People's HospitalShenzhen, Guangdong, ChinaRecruiting
Jiangsu Cancer Institute & HospitalNanjing, Jiangsu, ChinaRecruiting
The Affiliated Hospital of Qingdao UniversityQingdao, Shandong, ChinaRecruiting
Tianjin Medical University Cancer Institute & HospitalTianjing, Tianjing, ChinaRecruiting
Shanghai Chest Hospital, Shanghai Jiao Tong University Medicine of SchoolShanghai, ChinaRecruiting
Hôpital Saint Joseph MarseilleMarseille, FranceRecruiting
University Hospital, RouenRouen, FranceRecruiting
Azienda Ospedaliera di CosenzaCosenza, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07528066