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Study identifier: NCT07527208 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Meta-SHIFT Study: How Metabolic Shift Shapes Human Immunometabolism - a Fasting Trial

Condition: Fasting  ·  Sponsor: Cornell University

PhaseNA
Planned participants28
Who can joinAll sexes, 18 Years to 40 Years
Healthy volunteersYes

About this study

During fasting, the body shifts from using carbohydrates to relying more on fat as its main source of energy. This process is known as the 'metabolic shift'. Fat tissue helps supply this energy by breaking down stored fat into fatty acids, which are released into the bloodstream and transported to organs throughout the body. In addition to fatty acids, many other substances in the blood (such as metabolites) change during fasting to help maintain normal body function. Immune cells also circulate in the blood and play an important role in protecting the body against infections and diseases such as cancer. However, it is not yet well understood how the metabolic shift during fasting affects immune cell function. The purpose of this study is to investigate how 24 hours of fasting influences immune cell metabolism and function.

This description comes directly from the study's public registry record.

Talk to the study team

Larissa van der Zon, MS  ·  607-255-4045  ·  meta-shift@cornell.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Human Metabolic Research Unit, Division of Nutritional Sciences. Cornell UniversityIthaca, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07527208