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Study identifier: NCT07525505 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Nigella Sativa Oil for Eczematous Otitis Externa

Condition: Eczema/Atopic Dermatitis · Otitis Externa  ·  Sponsor: Bezmialem Vakif University

PhaseNA
Planned participants85
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Eczematous otitis externa is a common inflammatory condition of the external auditory canal characterized by itching, discomfort, discharge, and pain. Topical corticosteroids are widely used for treatment; however, alternative therapies with fewer side effects are of increasing interest. This study aims to compare the efficacy of Nigella sativa (black seed) oil and mometasone furoate ear drops in the treatment of eczematous otitis externa. Nigella sativa is a natural product with known anti-inflammatory and antimicrobial properties. In this randomized, controlled clinical trial, adult patients with eczematous otitis externa will be assigned to receive either Nigella sativa oil or mometasone furoate ear drops for 10 days. Clinical symptoms and inflammatory findings will be evaluated at baseline and after treatment. The objective of this study is to determine whether Nigella sativa oil is an effective and safe alternative to topical corticosteroid therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Nazan Degirmenci, MD,Assoc. Prof.  ·  +90(212) 523 22 88  ·  nzndegirmenci@hotmail.com

muhammed said ekinci, resident MD  ·  +90(212) 523 22 88  ·  muhammed.ekinci@bezmialem.edu.tr

Always discuss trial participation with your own doctor first.

Locations (1)

Bezmialem Vakif UniversityIstanbul, Fatih, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07525505