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Study identifier: NCT07524777 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Ganoderma Spores Modulate the Gut-Brain Axis

Condition: Depression · Thyroid Cancer  ·  Sponsor: Ling Zhiqiang

PhaseNA
Planned participants300
Who can joinFemale, 18 Years to 80 Years
Healthy volunteersNo

About this study

This study aims to investigate whether Sporoderm-removed Ganoderma lucidum spore powder (RGLS) ameliorates depression in thyroid cancer patients through gut-brain axis modulation, and to elucidate the underlying microbial and metabolic mechanisms. This 3-month randomized, double-blind, placebo-controlled trial will enroll 300 postoperative papillary thyroid carcinoma patients with depressive symptoms (HAMD-24 ≥ 8). Participants will be randomly assigned(2 : 1) to receive RGLS (4 g/day) or matched placebo.

This description comes directly from the study's public registry record.

Talk to the study team

Zhiqiang Ling  ·  +86-571-88122423  ·  lingzq@zjcc.org.cn

Jinbiao Shang  ·  shangjb@zjcc.org.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Zhejiang Cancer HospitalHangzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07524777