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Study identifier: NCT07524452 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Becotatug Vedotin (MRG003) in Combination With PD-1 Inhibitor Versus PD-1 Inhibitor for the Treatment of EGFR-positive, CPS≥1 Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma

Condition: Locally Advanced Head and Neck Squamous Cell Carcinoma  ·  Sponsor: Ming-Yuan Chen

PhasePhase 3
Planned participants430
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study is a randomized, open-label, multicenter phase III trial designed to systematically evaluate the efficacy and safety of perioperative neoadjuvant and adjuvant therapy with Becotatug vedotin in combination with PD-1 inhibitor versus PD-1 inhibitor alone in patients with EGFR-positive, CPS ≥ 1 resectable locally advanced head and neck squamous cell carcinoma .

This description comes directly from the study's public registry record.

Talk to the study team

Mingyuan Chen  ·  +86 18124188280  ·  chmingy@mail.sysu.edu.cn

Rui You  ·  +86 13580439820  ·  your5@mail.sysu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

The Fifth Affiliated Hospital,Sun Yat-sen UniversityZhuhai, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07524452