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Study identifier: NCT07523633 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Semaglutide on Cannabis Use in Adults With Cannabis Use Disorder

Condition: Cannabis Use Disorder · Cannabis Use Disorders · Cannabis Abuse  ·  Sponsor: Anders Fink-Jensen, MD, DMSci

PhasePhase 2
Planned participants100
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

The HASHTAG Study is investigating whether the medicine semaglutide can help adults with cannabis use disorder (CUD) reduce their cannabis use. Participants will be randomly assigned to receive either semaglutide or a placebo. The first 50 participants will have functional brain scans (fMRI) to investigate how the brain responds to cannabis-related cues. The main outcome after 20 weeks is whether semaglutide reduces cannabis use compared to placebo. Changes in brain activity in response to cannabis cues will be explored as a secondary outcome.

This description comes directly from the study's public registry record.

Talk to the study team

Maria E Marstrand, MD  ·  +4520896532  ·  maria.erlang.marstrand@regionh.dk

Anders Fink-Jensen, MD, DMSc  ·  +4522755843  ·  anders.fink-jensen@regionh.dk

Always discuss trial participation with your own doctor first.

Locations (1)

Psychiatric Center Copenhagen, Frederiksberg HospitalFrederiksberg, DenmarkRecruiting

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Source record: clinicaltrials.gov/study/NCT07523633