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Study identifier: NCT07522879 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Becotatug Vedotin (MRG003) Combined With Epirubicin as Neoadjuvant Therapy for EGFR-Positive, Unresectable Recurrent Sinonasal Adenoid Cystic Carcinoma

Condition: Adenoid Cystic Carcinoma · Sinonasal Carcinoma  ·  Sponsor: Eye & ENT Hospital of Fudan University

PhasePhase 2
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This prospective, multicenter clinical study aims to evaluate the efficacy and safety of neoadjuvant therapy with MRG003 (Becotatug vedotin) combined with epirubicin in patients with EGFR-positive, unresectable recurrent sinonasal adenoid cystic carcinoma (SNACC). The primary question is whether this combination can achieve a sufficient objective response rate (ORR) to enable subsequent radical surgery or improve disease control.

This description comes directly from the study's public registry record.

Talk to the study team

Quan Liu, Director  ·  8615001959681  ·  liuqent@163.com

Wanpeng Li, mid-level  ·  8613262856870  ·  18879117831@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Eye & ENT Hospital of Fudan UniversityShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07522879