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Study identifier: NCT07520344 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Wearable Photoplethysmography for Non-invasive Hydration Assessment

Condition: Hydration Status  ·  Sponsor: PepsiCo Global R&D

PhaseNA
Planned participants30
Who can joinAll sexes, 18 Years to 45 Years
Healthy volunteersYes

About this study

Hydration status during exercise is often determined by measuring body mass change, fluid intake and urine output. However, obtaining these measurements can be an invasive, time-consuming process. Hydration status may be detectable by analyzing blood flow patterns of the superficial (just under the skin) blood vessels. Wearable devices are now abundant among the general population, and despite attempts from several groups, a hydration status metric based on noninvasive wearable device metrics has not been developed. With wearables, a light source connected to an optical sensor transmits and reflects light through the body. The light sensor detects absorption of the light based on wavelength measurements of the detected light. Absorption of specific wavelengths of light energy is dependent upon the amount of oxygenated blood in the vessels. When the vessels expand and relax, the amount of blood volume in the observed tissue increases and decreases potentially causing a shift in the photoplethysmography (PPG) wave detected by the wearable. The shift in the shape of the PPG wave may be detected in a way that indicates the relative change in tissue hydration levels. However, to our knowledge, no wrist worn device that utilizes PPG has been successfully able to predict hydration status. Therefore, this study aims to utilize photoplethysmography (PPG) technology in a wearable device to accomplish this approach to hydration monitoring.

This description comes directly from the study's public registry record.

Talk to the study team

Anthony Wolfe  ·  574-315-5901  ·  anthony.wolfe@pepsico.com

Always discuss trial participation with your own doctor first.

Locations (2)

PepsiCo R&DFrisco, Texas, United StatesRecruiting
PepsiCo R&DPlano, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07520344