Condition: Esophageal Squamous Cell Carcinoma · Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma · Sponsor: Sichuan University
Malnutrition is highly prevalent in patients with upper gastrointestinal tumors, which may negatively impact treatment tolerance and anti-tumor immune responses. This study aims to evaluate the efficacy and safety of intensive enteral nutritional support in patients with locally advanced unresectable esophageal squamous cell carcinoma (ESCC) undergoing conversion therapy. Participants receiving PD-1 inhibitors combined with chemotherapy will be randomly assigned to either intensive nutritional support or standard care. The primary goal is to determine if intensive nutritional support can improve the pathological complete response (pCR) rate after subsequent surgery.
This description comes directly from the study's public registry record.
Zhenyu Ding, PhD · +86-189-8060-1957 · dingzhenyu@scu.edu.cn
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| West China Hospital, Sichuan University | Chengdu, Sichuan, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07519486