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Study identifier: NCT07518602 Synced from ClinicalTrials.gov · July 29, 2026
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Efficacy and Safety of Chidamide+Sintilimab+Bev as Second-Line Therapy in Advanced Extrapulmonary Neuroendocrine Carcinoma

Condition: Extrapulmonary Neuroendocrine Carcinoma (EP-NEC)  ·  Sponsor: Sun Yat-sen University

PhasePhase 2
Planned participants34
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a single-arm, multicenter phase Ⅱ study to evaluate the therapeutic efficacy and safety of chidamide + sintilimab + bevacizumab in subjects with advanced extrapulmonary neuroendocrine carcinoma who have failed first-line standard therapy. The primary purpose is to assess the objective response rate (ORR) of chidamide + sintilimab + bevacizumab in the above-mentioned subjects, with a planned enrollment of 34 subjects with advanced extrapulmonary neuroendocrine carcinoma who have failed first-line standard therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Feng Wang, MD, PhD  ·  +86 020 87343795  ·  wangfeng@sysucc.org.cn

Zhiqiang Wang, MD, PhD  ·  +86 02087340776  ·  wangzhq@sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sun Yat-sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07518602