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Study identifier: NCT07518043 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of HLX18 vs. OPDIVO® in Multiple Resected Solid Tumors

Condition: Esophageal and/or Cardia Cancer · Melanoma · Urothelial Carcinoma (UC)  ·  Sponsor: Shanghai Henlius Biotech

PhasePhase 1
Planned participants174
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

This is a multicenter, randomized, double-blind, parallel-controlled phase I clinical study to evaluate the similarity in PK profile, efficacy, safety and immunogenicity of HLX18 and OPDIVO® in patients with resected esophageal or gastroesophageal junction cancer (EC/GEJC), melanoma (MEL), or urothelial carcinoma (UC).

This description comes directly from the study's public registry record.

Talk to the study team

Chang Chen  ·  +86 138 1686 9003  ·  chenthoracic@163.com

Always discuss trial participation with your own doctor first.

Locations (7)

Fujian Medical University Union HospitalFuzhou, ChinaRecruiting
The First Affiliated Hospital Zhejiang University School Of MedicineHangzhou, ChinaRecruiting
The First Affiliated Hospital of Henan University of Science & TechnologyLuoyang, ChinaRecruiting
The Second Hospital of Tianjin Medical UniversityTianjin, ChinaRecruiting
The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, ChinaRecruiting
Union Hospital, Tongji Medical College,Huazhong University of Science and TechnologyWuhan, ChinaRecruiting
The Second Affiliated Hospital of Xi'an Jiaotong UniversityXi'an, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07518043