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Study identifier: NCT07517575 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pharmacokinetics, Efficacy and Safety of Olokizumab In Patients With Juvenile Idiopathic Arthritis

Condition: Juvenile Idiopathic Arthritis  ·  Sponsor: R-Pharm International, LLC

PhasePhase 2
Planned participants71
Who can joinAll sexes, 2 Years to 17 Years
Healthy volunteersNo

About this study

The primary objective of this study is to evaluate the pharmacokinetics (PK) of olokizumab (OKZ) in patients with polyarticular juvenile idiopathic arthritis aged \>2 and \<18 years in two doses (64 mg or 48 mg every 4 weeks) depending on patient's weight. Secondary objectives are to evaluate the pharmacodynamic (PD) profile, the long-term efficacy and safety of olokizumab in patients with polyarticular juvenile idiopathic arthritis aged \>2 and \<18 years.

This description comes directly from the study's public registry record.

Talk to the study team

Anna Karpenko  ·  +7 (495) 956-79-37  ·  karpenko@rpharm.ru

Darya Bukhanova  ·  +7 (495) 956-79-37  ·  bukhanova@rpharm.ru

Always discuss trial participation with your own doctor first.

Locations (14)

Federal State Budgetary Educational Institution of Higher Education "Kazan State Medical University" of the Ministry of Health of the Russian FederationKazan', RussiaRecruiting
Federal State Budgetary Scientific Institution "V.A. Nasonova Research Institute of Rheumatology"Moscow, RussiaRecruiting
State Budgetary Institution of Healthcare of the City of Moscow "Morozovskaya Children's City Clinical Hospital of the Moscow City Health Department" (GBUZ "Morozovskaya DGBK DZM")Moscow, RussiaRecruiting
Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University)Moscow, RussiaRecruiting
Federal State Autonomous Institution "National Medical Research Center for Children's Health" of the Ministry of Health of the Russian FederationMoscow, RussiaRecruiting
Limited Liability Company "Healthy Family Medical Center"Novosibirsk, RussiaRecruiting
Federal State Budgetary Educational Institution of Higher Education "Rostov State Medical University" of the Ministry of Health of the Russian FederationRostov-on-Don, RussiaRecruiting
LLC "Medical Technologies"Saint Petersburg, RussiaRecruiting
Federal State Budgetary Educational Institution of Higher Education "Saratov State Medical University named after V.I. Razumovsky" of the Ministry of Health of the Russian FederationSaratov, RussiaRecruiting
Limited Liability Company "Scientific Medical Center of General Therapy and Pharmacology" (LLC "TERAPHARM")Stavropol, RussiaRecruiting
State Budgetary Healthcare Institution of the Samara Region "Tolyatti City Clinical Hospital No. 5"Tolyatti, RussiaRecruiting
Federal State Budgetary Educational Institution of Higher Education "Bashkir State Medical University" of the Ministry of Health of the Russian FederationUfa, RussiaRecruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07517575