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Study identifier: NCT07517445 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Bactericidal Activity and Safety of Nicotinamide in Combination With Bedaquiline, Pretomanid, and Linezolid in Drug-susceptible Pulmonary Tuberculosis

Condition: Drug Susceptible Pulmonary Tuberculosis  ·  Sponsor: Gates Medical Research Institute

PhasePhase 2
Planned participants165
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

The purpose of this study is to determine if nicotinamide in combination with bedaquiline, pretomanid, and linezolid, is safe and effective in treating drug-susceptible pulmonary tuberculosis.

This description comes directly from the study's public registry record.

Talk to the study team

Gates MRI  ·  +857-702-2108  ·  Clinical.trials@gatesmri.org

Gates MRI  ·  +1-866-789-5757  ·  Clinical.trials@gatesmri.org

Always discuss trial participation with your own doctor first.

Locations (4)

Wits RHI - Shandukani ResearchJohannesburg, Gauteng, South AfricaRecruiting
The Aurum Institute Clinical Research Site - PretoriaPretoria, Gauteng, South AfricaRecruiting
TASK Clinical Research CentreCape Town, Western Cape, South AfricaRecruiting
UCT Lung Institute (Pty) Ltd (Centre for TB Research Innovation)Cape Town, Western Cape, South AfricaRecruiting

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Source record: clinicaltrials.gov/study/NCT07517445