Condition: Age - Related Macular Degeneration (AMD) · Sponsor: Maximilian Pfau
This monocentric prospective longitudinal observational study will validate fundus-tracked dark adaptometry as an endpoint for future treatment trials in early and intermediate age-related macular degeneration (AMD). The study will characterize normative cone- and rod-mediated dark adaptation parameters in healthy volunteers, assess test-retest reliability, quantify sensitivity to change over time, evaluate diagnostic and prognostic validity against AMD stage and structural progression, and investigate imaging-, biomarker-, and genetics-based determinants of impaired dark adaptation.
This description comes directly from the study's public registry record.
Maximilian Pfau, MD, FEBO · +49 228 287 15505 · maximilian.pfau@ukbonn.de
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| Department of Ophthalmology, University Hospital Bonn | Bonn, Germany | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07515521