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Study identifier: NCT07515235 Synced from ClinicalTrials.gov · July 29, 2026
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DMD Gene Variants and Cardiac Dysfunction in Young Males With Dystrophinopathies

Condition: Duchenne Muscular Dystrophy (DMD) · Becker Muscular Dystrophy · Cardiomyopathy  ·  Sponsor: Aristotle University Of Thessaloniki

PhaseN/A
Planned participants65
Who can joinMale, 2 Years to 24 Years
Healthy volunteersNo

About this study

The goal of this observational study is to investigate whether the type, location, and extent of pathogenic variants in the DMD gene are associated with cardiac dysfunction in male children, adolescents, and young adults with dystrophinopathies. The study also evaluates whether cardiac biomarkers and electrocardiographic findings can facilitate the early identification of cardiac involvement. Participants will undergo electrocardiography, blood sampling for cardiac biomarker assessment, and transthoracic echocardiography, with cardiac dysfunction evaluated using ejection fraction (EF) and global longitudinal strain (GLS).

This description comes directly from the study's public registry record.

Talk to the study team

Ioanna Agathokleous, MD, MSc, PhD(c)  ·  +30 2313303534  ·  iagatho@auth.gr

Always discuss trial participation with your own doctor first.

Locations (1)

AHEPA University Hospital of ThessalonikiThessaloniki, GreeceRecruiting

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Source record: clinicaltrials.gov/study/NCT07515235