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Study identifier: NCT07514650 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Validation of a Regional Citrate Anticoagulation Protocol in Critically Ill Patients on Continuous Renal Replacement Therapy

Condition: Acute Kidney Injury · ICU Patients · Continuous Renal Replacement Therapy (CRRT)  ·  Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

PhaseNA
Planned participants43
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The objective of this study is to evaluate the effectiveness of a modified continuous renal replacement therapy (CRRT) protocol in maintaining electrolyte balance in adult patients with acute kidney injury (AKI) admitted to the intensive care unit (ICU). The study assesses whether the use of continuous venovenous hemodiafiltration (CVVHDF) with post-filter replacement under citrate anticoagulation reduces electrolyte losses and the need for electrolyte supplementation compared with standard dialytic CRRT. Participants receiving standard CRRT will be compared with those treated with the modified protocol. The duration of participation corresponds to the period during which CRRT is required. Data collection will cease once CRRT is discontinued.

This description comes directly from the study's public registry record.

Talk to the study team

Ana Jiménez Valenzuela, Nurse  ·  +34935537796  ·  ajimenezva@santpau.cat

Alejandra Espinosa Guerrero, Clinical Operations Head  ·  +34 935537796  ·  uicec@santpau.cat

Always discuss trial participation with your own doctor first.

Locations (1)

Hospital de la Santa Creu i Sant PauBarcelona, Barcelona, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT07514650